Ultimate ultrasound visibility


Encapson is a medical technology company with the mission to improve patient care through innovative echogenic coating solutions for medical devices. Sono-Coat™ is an echogenic coating technology that significantly improves the ultrasound visibility of medical devices in the body leading to better patient outcomes. The unmatched ultrasound visibility of Sono-Coat™ enables doctors carrying out difficult minimally invasive procedures.

Encapson is the frontrunner in echogenic coating solutions. We work closely together with the medtech industry and experienced clinicians to develop state of the art visibility solutions for precision guided medical procedures.


Standard medical devices have a poor visibility in ultrasound imaging, which creates a risk when carrying out interventions. Sono-Coat™ catheters and needles are clearly visible in the image, allowing for effortless location from any possible angle. Sono-Coat™ technology also enables precise targeting of objects in deeper tissue structures (e.g. liver and kidney biopsies) and supports the physician in performing accurate, safe and error-free ultrasound-guided minimally invasive procedures.


Sono-Coat™ is based on a coating matrix of acoustically reflective microspheres that enhance ultrasound reflection, independent of the angle of the medical device.


As front-runner in echogenic coating solutions Encapson has defined a new standard for ultrasound visibility in imaging minimally invasive procedures. In a comparative study, 60 endoscopists and interventional radiologists performed a blind review of the ultrasound visibility of 10 different echogenic biopsy needles (laser-etched, dimpled, sand-blasted and Sono-Coated™). The Sono-Coat™ needle outperformed (p<0.01) currently available needles and was ranked number 1 in ultrasound visibility. The results have been published in GIE (PMID: 26873530).

Sono-Coat™ technology can be applied to polymer catheters and steel, nitinol or titanium needles. Sono-Coat™ is biocompatible, temperature resistant for ablation therapy and can be overcoated with lubricious, anti-microbial and anti-thrombogenic coatings without loss of echogenicity. Encapson is ISO13485:2016 certified and recently deployed a cutting-edge production unit for the automated application of Sono-Coat™.


Encapson already established multiple research and contract manufacturing collaborations. Our goal is to work together with medtech companies, clinicians and research institutes to increase the clinical value of Sono-Coat™. Our coating systems facilitate the work of interventional clinicians in applications such as regional anesthesia (needles and catheters), biopsies, RF/RM/Cryo ablation, central lines (CVC, PICC), specialty catheters, angioplasty, transseptal puncture and mitral valve repair. If you would like to explore how integration of Sono-Coat™ technology can support you in developing novel applications, please contact us at: info@encapson.com


Heico Breek, MD, MBA
Before joining Encapson, Heico Breek held senior management positions in both Europe and the United States at Aventis Pharma as Vice-President Global Marketing for Aventis’ Arthritis and Bone Group. He was General Manager of Aventis AB in Sweden. After moving to biotech he held the position of Chief Commercial Officer at Tigenix NV in Belgium. Upon his return to the Netherlands he was appointed CEO of ACS Biomarker. Heico holds a Medical Degree from the VU University Amsterdam and an executive MBA from Erasmus University Rotterdam.
Lee Ayres, PhD
Lee Ayres is co-founder of Encapson and led the development of the Sono-Coat™ technology. He has built an extensive industry and academic network focused on developing echogenic solutions for medical devices. Lee is responsible for managing day to day operations and business development. He also leads the development of new applications and product innovations. Lee holds a degree in Chemistry and Management in Industry from University of York and a PhD from the Radboud University of Nijmegen in Synthetic Polymer Chemistry.
Bram Pape, PhD
Bram Pape obtained a PhD from the Eindhoven University of Technology in 2015, studying the development of biomaterials for regenerative medicine and drug delivery. He gained experience as project leader and R&D engineer in the pharmaceutical and medical industry at FeyeCon Carbon Dioxide Technologies, Océ Technologies and TMC. Bram joined Encapson in 2019, where he is responsible for managing day to day operations and product development. Next to his PhD, he holds a master’s degree in Chemistry from the Radboud University Nijmegen.


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Encapson BV
Institutenweg 25A
7521 PH Enschede
The Netherlands

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Tel: +31 24 7110330

Encapson B.V.

Chamber of Commerce: 09142910
VAT number: NL814467921B01